Daily Newsletter March 30, 2012
Evolution Friday!
Please read the following article on mammalian gene expression. It is a short, and fairly simple, open source article.Read the following two articles Neutral Theory.
Daily Challenge:
Evolution has its base in genetics. All variation starts with mutation. The addition, deletion or change in the nucleotide sequence of a coding region can result in protein changes. Any mutation, if it has an expressed effect, then becomes subject to the mechanism of Natural Selection.
A great example of this nucleotide alteration is seen in Sickle Cell Anemia. A change in one nucleotide causes a conformational change in the beta-hemoglobin chain, which causes the entire expression of the disease.
Your task today is to discuss the relationship DNA changes and Gene Expression has with evolution. Sit with the concept for a moment, and come up with a coherent discussion. Feel free to use models such as Sickle Cell Anemia. Remember, this alteration in gene expression sets up the diversity of the population. Natural Selection then acts on the new phenotype.
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